Modern extraction process for food analysis

Food sample preparation often involves:
  • Time-consuming and multi-step extraction methods
  • Matrix-dependent procedures requiring method adjustments
  • High solvent consumption and operating costs
  • Limited productivity due to long extraction cycles
  • Complex workflows involving multiple techniques and instruments
Traditional techniques such as Soxhlet and automated extraction systems are still widely used, but they rely on long processing times and large volumes of reagents, often requiring different methods and setups depending on the application. To overcome these limitations, Milestone has developed the ETHOS X and ETHOS X LEAN microwave platforms, providing a modern approach to food extraction workflows. These platforms enable faster analysis, reduced solvent consumption, and simplified laboratory operations across a wide range of food applications.
ETHOS X and ETHOS X LEAN
Faster total fat determination
Combined hydrolysis and extraction.
Simplified workflow
One method for different food matrices without re-optimization.
Safe operation
Closed-vessel system reduces operator exposure to reagents.
Reliable results
Controlled conditions ensure consistent performance across samples.
Beyond total fat analysis
Expand to FAMEs, MOAH/MOSH, and organic contaminants.
  • Success story

    total fat determination method
    At Eurofins Scientific in Nantes, France, the lab needs to reduce analysis time on over 200 samples per day to produce results faster for their clients.
  • Success story

    De Heus
    De Heus Animal Nutrition invested in ETHOS X microwave extraction systems to performs total fat determination on several feed samples in a fraction of the time with reduced solvent usage and disposal.
  • Application Report

    gravimetric fat determination
    Download our valuable resources for Total Fat, Crude Fat and Fatty acid methyl esters (FAME) determinations.

TOTAL FAT DETERMINATION
MADE EFFICIENT

Hydrolisis and Extraction at once

The ETHOS X and ETHOS X LEAN platforms apply microwave heating and closed-vessel technology for total fat determination, enabling a modern approach to food sample preparation. Hydrolysis and extraction are performed in a single step, significantly simplifying the overall process. Unlike traditional methods, which require multiple steps and matrix-dependent procedures, the ETHOS platforms use a single approach applicable to a wide range of food and feed samples. This reduces method development, minimizes operator intervention, and ensures consistent performance across different matrices. Samples and reagents are placed directly into the closed vessels, where microwave heating and controlled conditions enable efficient hydrolysis and extraction. The process is automatically managed, ensuring reproducible results while reducing handling steps and overall analysis time.
1 - Weighing step on the hydrolysis/ extraction vessel

1 - Weighing step on the hydrolysis/ extraction vessel

2 - Evaporation step

2 - Hydrolysis/Extraction step

3 - Data processing

3 - Data processing

Faster results with lower solvent consumption

Compared to traditional techniques such as Soxhlet and automated extraction systems, microwave-assisted extraction signifi cantly reduces analysis time. Hydrolysis and extraction are combined into a single step, enabling laboratories to process multiple samples in a shorter time and improve overall turnaround. The ETHOS X and ETHOS X LEAN platforms enable simultaneous processing of multiple samples in a single run, supporting effi cient laboratory operations. This approach increases daily sample throughput while reducing operator intervention and manual handling steps.
Improved Workflow & Productivity
The use of closed-vessel technology reduces reagent and solvent consumption compared to conventional methods. Lower solvent usage, combined with shorter processing times and simplifi ed workflows, contributes to a reduced cost per sample and more sustainable laboratory operations. The accuracy of the extraction process is confi rmed by results obtained on certified reference materials, demonstrating excellent agreement with reference values across different food matrices.
Lower cost per sample
Total fat determination on several CRMs and Quality control materials

BEYOND TOTAL FAT DETERMINATION

FATTY ACID METHYL ESTERS (FAMES)

The ETHOS X platforms enable direct extraction and derivatization of fatty acids within a single workflow, eliminating separate preparation steps. This approach simplifi es fatty acid profi ling, reduces analysis time, and improves reproducibility compared to traditional multi-step procedures.

MINERAL OIL HYDROCARBONS (MOAH & MOSH)

Microwave-assisted extraction supports the simultaneous saponifi cation and extraction of mineral oil hydrocarbons from complex food matrices. The controlled conditions reduce sample preparation time and improve repeatability, simplifying a typically labor-intensive and multi-step workflow, reducing preparation time from several hours to less than one hour.

ORGANIC CONTAMINANTS (PAHS, DIOXINS, PCBS)

The ETHOS X platforms enable effi cient extraction of organic contaminants using closed-vessel microwave technology. Compared to conventional techniques such as Soxhlet or pressurized liquid extraction, this approach reduces solvent consumption and extraction time while maintaining comparable recovery and reproducibility, signifi cantly faster than Soxhlet and PLE methods.

Greennovation

for your lab

Milestone is the only sample preparation company with a true and proven sustainability commitment.

Microwave-assisted extraction

Conventional methods like Soxhlet are not only solvent-intensive but energy-heavy and time-consuming. The ETHOS X microwave platform supports the development of solvent-reduced or solvent-free protocols via microwave-assisted extraction (MAE).
Applications range from:
  • Food and nutraceuticals
  • Environmental matrices
  • Plant materials
  • Plastic additives and pollutants
  • Cosmetic and pharmaceutical ingredients

Microwave energy enables efficient extraction using minimal volumes of solvents. The resulting protocols are faster, cleaner, and more environmentally responsible.
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